UCLA scientists
have uncovered a new way to scan brain tumors
and predict which ones will be shrunk by
the drug Avastin — before the patient
ever starts therapy. By linking high water
movement in tumors to positive drug response,
the UCLA team predicted with 70
percent accuracy which patients' tumors
were the least likely to grow six months
after treatment.
Bronnie McNabb, 57,
considers himself lucky. When his aggressive
brain cancer returned after chemotherapy
and radiation, his UCLA doctor prescribed
the off-label use of Avastin, a drug shown
to quell cancers in the breast, colon and
lung.
One month
later, McNabb's tumors had shrunk by 95
percent. Subsequent brain scans show no
trace of his cancer at all. The former marathon
runner, ordained minister and father of
two says he hasn't felt this good since
his diagnosis last winter.
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